KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP2K6
All Species:
11.52
Human Site:
S26
Identified Species:
21.11
UniProt:
P52564
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52564
NP_002749.2
334
37492
S26
A
F
E
Q
P
Q
T
S
S
T
P
P
R
D
L
Chimpanzee
Pan troglodytes
Q9XT09
393
43428
E41
Q
K
K
L
E
E
L
E
L
D
E
Q
Q
R
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851023
334
37590
S26
A
F
E
Q
P
Q
T
S
S
T
P
P
R
D
L
Cat
Felis silvestris
Mouse
Mus musculus
P70236
334
37414
S26
A
F
E
Q
P
Q
T
S
S
T
P
P
R
D
L
Rat
Rattus norvegicus
Q4KSH7
419
47517
P67
S
S
P
Q
H
P
T
P
P
S
R
P
R
H
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511595
352
40240
N42
T
I
K
P
P
V
S
N
P
T
P
P
R
N
L
Chicken
Gallus gallus
Q90891
398
44059
E43
Q
K
K
L
E
E
L
E
L
D
E
Q
Q
K
K
Frog
Xenopus laevis
Q07192
446
50082
S95
A
I
R
K
L
E
T
S
Y
Q
K
Q
D
L
R
Zebra Danio
Brachydanio rerio
Q9DGE0
361
40575
A53
V
F
E
K
P
A
P
A
P
T
P
P
R
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477162
334
38176
L26
A
I
V
P
P
R
N
L
D
S
R
A
T
I
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20347
363
41178
S46
E
S
V
L
R
S
L
S
T
G
T
L
K
Y
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S7U9
363
39830
Q28
S
I
T
K
F
L
T
Q
S
G
T
F
K
D
G
Baker's Yeast
Sacchar. cerevisiae
P08018
668
72701
K120
Q
V
V
Q
A
S
S
K
S
T
L
K
N
V
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32
N.A.
98.8
N.A.
97.9
38.6
N.A.
75.2
34.4
43.5
80.6
N.A.
58.6
N.A.
38.2
N.A.
Protein Similarity:
100
47.8
N.A.
99
N.A.
99
53.7
N.A.
85.5
51.5
56
85.8
N.A.
74.8
N.A.
56.2
N.A.
P-Site Identity:
100
0
N.A.
100
N.A.
100
26.6
N.A.
40
0
20
60
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
20
N.A.
100
N.A.
100
46.6
N.A.
66.6
20
33.3
73.3
N.A.
26.6
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.9
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.1
36
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
0
0
0
8
8
0
8
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
16
0
0
8
39
0
% D
% Glu:
8
0
31
0
16
24
0
16
0
0
16
0
0
0
0
% E
% Phe:
0
31
0
0
8
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
8
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
31
0
0
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
16
24
24
0
0
0
8
0
0
8
8
16
8
16
% K
% Leu:
0
0
0
24
8
8
24
8
16
0
8
8
0
8
47
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
8
8
0
0
0
0
8
8
0
% N
% Pro:
0
0
8
16
47
8
8
8
24
0
39
47
0
0
8
% P
% Gln:
24
0
0
39
0
24
0
8
0
8
0
24
16
0
8
% Q
% Arg:
0
0
8
0
8
8
0
0
0
0
16
0
47
8
8
% R
% Ser:
16
16
0
0
0
16
16
39
39
16
0
0
0
0
0
% S
% Thr:
8
0
8
0
0
0
47
0
8
47
16
0
8
0
0
% T
% Val:
8
8
24
0
0
8
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _